A full slate of Sunday night games is headlined by the Green Bay Packers taking on the Tampa Bay Buccaneers, as two of the greatest quarterbacks of all time face off.
Elsewhere, the Pittsburgh Steelers host the Cleveland Browns in what is sure to be a full-blooded divisional clash.
Our Odds Pick – Tampa to beat Green Bay – 21/20 at bet365
For Buccaneers quarterback Tom Brady to still be playing at the highest level at the age of 43 is remarkable, particularly as he plays in a position where 20 stone behemoths are regularly trying to smash his face in!
And his stats this season indicate that Brady has more in the tank, as he’s tenth in passing yardage and fifth in number of TDs thrown.
Over in Green Bay, the foundation of their 100% record has been their running attack.
Running Back Aaron Jones has averaged over 93.5 yards and a touchdown per game.
However, Tampa’s rush defence is one of the best in the NFL, allowing opposing teams an average of just 58.4 yards on the ground per game.
They’re also fourth in number of sacks, with 17 from five games.
And if the Bucs defence have had their Weetabix then it could an uncomfortable night for the Packers.
Our Odds Pick – Under 50.5 points, Pittsburgh v Cleveland – 10/11 at Paddy Power
Cleveland Browns fans normally endure, rather than enjoy games against the Pittsburgh Steelers.
And that’s because they have won just three of the last 29.
They will have their work cut out to add to that tally when they face a Steelers side who are 4-0.
Pittsburgh’s ferocious defence leads the league in rushing yards conceded, and is top four in passing yards allowed.
Which means that Browns QB Baker Mayfield and his Offensive Line may end up taking more hits than your credit card on Amazon Prime day.
However, the 4-1 Browns will be a big step up for the Steelers, who have faced a pretty soft schedule so far.
And in Myles Garrett they have one of the league’s premier pass rushers, who has already amassed six sacks.
So with defences seeming likely to dominate, we reckon a low scoring game could be in the offing.