Advertiser Disclosure
We want to bring you the best content and the best offers. Just so you know, we may collect compensation from the links on this page, and some of our reviewers are compensated for contributing content to this website.

NFL Odds & Betting – The Odds Manager Guide

While American Football is arguably the most popular sport in the USA, it also has a massive fanbase worldwide, with the season-ending Super Bowl having transcended the sport and become a genuine cultural phenomenon.

And with more ways to bet on it than there is padding on your average NFL player, there are plenty of opportunities to boost your bankroll.

Here at Odds Manager, we’ve got some big American Football fans, and that means we’ll always be there with the latest NFL news, views, and NFL betting odds including the latest Super Bowl odds.

Here are all the latest odds for the upcoming matches in the NFL.

Click on any odds to add it to your betslip or click on a fixture to see a comparison of odds from all the top bookies.

What To Watch In 2021

The biggest story of the 2020-21 season was Tom Brady winning his seventh Super Bowl ring, leading the Tampa Bay Buccaneers to victory over Patrick Mahomes and the Kansas City Chiefs.

Brady has said he will return next season, and once again the question will be whether the GOAT can bring it once again, at the age of 44.

We wouldn’t bet against him – would you?

Before we get to the next campaign though, there’s the NFL Draft in April.

And while there’s little doubt that Clemson QB Trevor Lawrence will be off to Jacksonville, there are many questions to answer about the landing spots for College Football’s finest.

And that means betting opportunities aplenty, so look out for our top Odds Picks ahead of the big event!

Our Top Welcome Offers For The NFL

Up To
Up To
Up To
Betfair Exchange

NFL Odds – What To Bet On

When it comes to betting on the NFL, there’s more choice than a Craft Beer Festival. And that’s thanks to there being at least 13 games every week, each with an enormous range of markets.

But what really singles out the NFL from a betting perspective is the statistics that are available to punters every week, giving you the edge in your battle with the bookies. 

Super Bowl Betting

The NFL season only runs from September to February, so if you’re backing the Super Bowl winner before the campaign starts then you don’t have long to wait to learn your fate!

And with the best prices on offer before the season starts, it pays to act early.

Handicap Betting

Let’s say you don’t just fancy a team to win, but to win comfortably.

So instead of backing them straight up at a very low price, you can back them to win by more than a certain amount of points, for a price that is generally even money or slightly lower.

It works the other way too in that you can bet on a certain team not to lose by more than a certain amount of points, which effectively gives you two ways to make money, either if they win, or lose narrowly.

Points Totals

When it comes to NFL clashes, sometimes you might not be confident of who the winner will be, but you’re convinced it’s going to be a high or low scoring game.

So you can back under or over a certain total and watch the touchdowns fly in with either joy or anger!


Among all the handicaps and points totals, let’s not forget the humble Acca, which is still a great way to make some cash, betting on the NFL.

You can mix and match handicaps and points totals for big-priced Acca’s.

But don’t forget that in any given week there are usually at least five or six clear favourites at low prices, just waiting to be added together, maybe with a cheeky Acca boost too!


At Odds Manager, we have had a look around and bwin have caught our eye, as they are giving you the opportunity to “Build A Bet”, meaning you can combine a number of single selections from the same NFL game into one Acca.
Given that the average NFL game is a backside-numbing three and a half hours long, in-play betting plays a massive part, with all the big-name bookies offering live odds on a wide range of markets.
Sky Sports show four live games a week, the Super Bowl and all playoff matches, as well as “Red Zone”, a live show every Sunday showing in-play highlights. But if you don’t have satellite TV you can also check out the NFL show every week on the BBC, along with the Super Bowl.